Treatment of Patients with Mild Hemophilia-A and Low Titer Inhibitor during Operations: Report of a Case

There is little data for the management of patients with mild hemophilia-A and inhibitors concerning prophylaxis before operations and in the postoperative period. We report a case of an adult with mild hemophilia-A and a low-titer inhibitor who successfully underwent hemorrhoidectomy without post-operative bleeding. An increased dose of F-VIII concentrate was given before operation and a bypassing agent with desmopressin were given after operation. The main challenge in that case was not to trigger the inhibitor and change the clinical phenotype to severe.